Recent Publications

    Complete List of Publications Can Be Found Here

    1. Wall, T.R.*; Henderson, B.J.*; Voren, G.; Wageman, C.R.; Deshpande, P.; Cohen, B.N.; Grady, S.R.; Marks, M.J.; Yohannes, D.; Bencherif, M.; Kenny, P.J.; and Lester, H.A. (2017) TC299423, a novel agonist for nicotinic acetylcholine receptors. Frontiers in Pharmacology. *, designates co-first authorship. DOI: 10.3389/fphar.2017.00641
    2. Henderson, B.J.; Wall, T.R.; Henley, B.M.; Kim, C.H.; McKinney, S.; and Lester, H.A. (2017) Menthol enhances nicotine reward-related behavior by potentiating nicotine-induced changes in nAChR function, nAChR upregulation, and DA neuron excitability. Neuropsychopharmacology. DOI: 10.1038/npp.2017.72
    3. Fox-Lee, A.M.; Henderson, B.J.; Richards, C.I. (2016) Utilizing pHluorin-tagged receptors to monitor subcellular localization and trafficking. J Vis Exp (121), e55466, DOI: 10.3791/55466
    4. Nichols, W.A.; Henderson, B.J.; Yu, C.Y.; Marotta, C.B.; Richards, C.I.; Dougherty, D.A.; Cohen, B.N.; and Lester, H.A. (2016) Suppression of low-sensitivity α4β2 nicotinic receptor expression by a mutation linked to autosomal dominant nocturnal frontal lobe epilepsy. PLoS ONE. 2016 Jun 23;11(6):e0158032. doi: 10.1371/journal.pone.0158032. eCollection 2016. PMID: 27336596
    5. Henderson, B.J.; Wall, T.; Henley, B.M.; Kim, C.H.; Nichols, W.A.; Xiao, C.; and Lester, H.A. (2016) Menthol alone upregulates midbrain nAChRs, alters nAChR subtype stoichiometry, alters dopamine neuron firing frequency, and prevents nicotine reward. J Neurosci. 36, 2957-2974. DOI: 10.1523/JNEUROSCI.4194-15.2016
    6. Srinivasan, R.; Henley, B.M.; Henderson, B.J.; Indersmitten, T.; Mckinney, S.; Deshpande, P.; Xiao, C.; and Lester, H.A. (2016) Smoking-relevant nicotine concentration inhibits the unfolded protein response in dopaminergic neurons. J Neurosci. 36, 69-75. DOI: 10.1523/JNEUROSCI.2126-15.2016
    7. Henderson, B.J. and Lester, H.A. (2015) Inside-out neuropharmacology of nicotinic drugs. Neuropharmacology. 96 Part B, 178-193. DOI:10.1016/j.neuropharm.2015.01.022.
    8. Xiao, C.; Miwa, J.M.; Henderson, B.J.; Wang, Y.; Deshpande, P.; McKinney, S.L.; Lester, H.A. (2015) Nicotinic receptor subtypes within selective circuits of the subthalamic nucleus. J Neurosci. 35, 3734-3746. DOI: 10.1523/JNEUROSCI.3528-14.2015. Featured Article
    9. Nichols, W.A.; Henderson, B.J.; Yu, C.Y.; Parker, R.L.; Richards, C.I.; Lester, H.A.; and Miwa, J.M. (2014) Lynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum. J Biol Chem. 289, 31423-31432. DOI:10.1074/jbc.M114.573667
    10. Srinivasan, R.; Henderson, B.J.; Lester, H.A.; and Richards, C.I. (2014) Pharmacological chaperoning of nAChRs: a new therapeutic target for Parkinson’s disease. Pharmacol Res. 83, 20-29. DOI: 10.1016/j.phrs.2014.02.005
    11. Henderson, B.J.; Srinivasan, R.; Nichols, W.N.; Dilworth, C.; Gutierrez, D.F.; McKinney, S.; Mackey, E.D.W.; Drenan, R.M.; Richards, C.I.; and Lester, H.A. (2014) Nicotine exploits a COPI-mediated process for chaperone-mediated upregulation of its receptors. J Gen Physiol. 143, 51-56. Cover Article (Link to Video Synopsis)

    Press releases and commentaries

    1. (Commentary) 2017. Lallai, V. and Fowler, C.D. More than just chillin’: interactive effects of menthol and nicotine in drug reward. Neuropsychopharmacology. DOI: 10.1038/npp.2017.107
    2. (Interview) 2017. Society for Research on Nicotine & Tobacco (SRNT) Scientist Spotlight: Dr. Brandon Henderson
    3. (Press Release) 2017. Speaking of Research. "Of Mice and Mint: Animal  research uncovers an unknown role for menthol in tobacco addiction." 
    4. (Press Release) 2014. New Scientist. Menthol increases nicotine addiction by tweaking brain. 
    5. (Press Release) 2014. Rockefeller University Press. Nicotine exploits COPI to foster addiction.
    6. (Commentary) Anand, R. COPI polices nicotine-mediated up-regulation of nicotinic receptors. J Gen Physiol. 143, 49-50.
    7. (Press Talk) Henderson, B.J. and Lester H.A. Why smokers of menthol cigarettes may find it harder to quit: menthol’s interaction with certain brain receptors may potentiate the addiction to nicotine. Society for Neuroscience Press Conference 2014: Legal Drugs of Abuse. Washington D.C., November 2014.